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Home - Products - Cell Cycle/DNA Damage - Topoisomerase - Coralyne chloride

Coralyne chloride

CAS No. 38989-38-7

Coralyne chloride ( —— )

Catalog No. M27970 CAS No. 38989-38-7

Coralyne chloride is a molecular rectifier based on fluorescent DNA, which is constructed into DNA double-stranded bodies by site-specific insertion.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Coralyne chloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Coralyne chloride is a molecular rectifier based on fluorescent DNA, which is constructed into DNA double-stranded bodies by site-specific insertion.
  • Description
    Coralyne chloride is a molecular rectifier based on fluorescent DNA, which is constructed into DNA double-stranded bodies by site-specific insertion.(In Vitro):There is synergism between Coralyne and Paclitaxel on proliferation and migration of breast cancer cell lines. This study also showed that combinational drug treatment decreased the expression of ki-67 and there was an increase in pro apoptotic factor Bax with decreased in expression of anti-apoptotic factor Bcl-2 in breast cancer cell lines with negligible effect on normal breast cell line.
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    Topoisomerase
  • Recptor
    Fungal
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    38989-38-7
  • Formula Weight
    399.9
  • Molecular Formula
    C22H22ClNO4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    [Cl-].COc1cc2cc[n+]3c(C)c4cc(OC)c(OC)cc4cc3c2cc1OC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.D Fabio Mercado, et al. Reaction Kinetics and Mechanisms of Organosilicon Fungicide Flusilazole With Sulfate and Hydroxyl Radicals. Chemosphere. 2018 Jan;190:327-336.
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